Goilean GV, Doma AO, Cristina RT, Dumitrescu E, Folescu M, Cocoș D, Muselin F.

Animal Husbandry and Fodder Production. 2025. Vol. 108. No. 4. Р. 41-47.

Original article

doi:10.33284/2658-3135-108-4-41

The values of some biochemical metabolic parameters in dairy cows supplemented with glycine

chelated minerals

George V Goilean¹, Alexandru O Doma², Romeo T Cristina³, Eugenia Dumitrescu⁴, Mihai Folescu⁵, Daiana Cocoș⁶, Florin Muselin^7,8

^{1,2,3,4,5,6,7}University of Life Sciences “King Michel I of Romania” from Timisoara (Timisoara, Romania)

⁸Working Group for Xenobiochemistry, Romanian Academy-Branch Timisoara (Timisoara, Romania)

²https://orcid.org/0000-0001-5252-6969

³https://orcid.org/0000-0002-5420-1516

⁴https://orcid.org/0000-0002-8346-6230

⁵https://orcid.org/0009-0005-5343-4245

⁶https://orcid.org/0009-0007-9308-626X

^7,8floinmuselin@usvt.ro, https://orcid.org/0000-0003-2907-4233

Abstract. The paper presents data regarding the impact of some trace mineral supplementation on some pmetabolic parameters of glycine chelated mineral supplemented dairy cows. The study was made on thirty Holstein multiparous dairy cows,  aging arround 62 ± 4.5 months that were divided randomly in two groups: C – Control receiving normal diet without glycine mineral supplementation and one experimental group (E) that received supplement of glycine chelated Cu, Zn, Mn and Fe as follows: 15 mg/kg Cu, 20 mg/kg Mn, 60 mg/kg Zn and, 100 mg/kg Fe, added in concentrate feed. The experiment was designed from day 30 of lactation until day 100 of lactation, and were assesed the potassium (K), phosphorus (P), glucose (Glu), aspartate aminotransferase (AST), alkaline phosphatase (ALP), total proteins (TP), albumin (ALB), urea (U), and creatinine (CRE). In the experimental group we observed significant (p<0.05) decrease of K and P, the non significant decrease of glicaemia and urea and, a significant (p<0,01) decrease of liver parameters such as Ast and ALP in cows supplemented with glycine minerals comparing with controls. There also noted a non significant increase of total pproteins (TP), ALB and CRE in experimental group compared to control. We conclude that supplementing the dairy cows whit chelated minerals could have a benificial role on main biochemical metabolic parameters, being necessary more studies on a long term period.

Keywords: metabolic parameters, dairy cows, supplements, minerals, glycine chelate

For citation: Goilean GV, Doma AO, Cristina RT, Dumitrescu E, Folescu M, Cocoș D, Muselin F. The values of some biochemical metabolic parameters in dairy cows supplemented with glycine chelated minerals. Animal Husbandry and Fodder Production. 2024;108(4):41-47. (In Russ.). https://doi.org/10.33284/2658-3135-108-4-41

Information about the authors:

George Vlad Goilean, PhD student, Department of Toxicology, Faculty of Veterinary Medicine, University of Life Sciences “King Michel I of Romania” from Timisoara, 300645, Timisoara, Romania, Calea Aradului 119.

Alexandru Octavian Doma, PhD, DVM, Assistant Professor, Faculty of Veterinary Medicine, University of Life Sciences “King Michel I of Romania” from Timisoara, 300645, Timisoara, Romania, Calea Aradului 119.

Romeo Teodor Cristina, PhD, DVM, Professor, Head of Department of Toxicology, Faculty of Veterinary Medicine, University of Life Sciences “King Michel I of Romania” from Timisoara, 300645, Timisoara, Romania, Calea Aradului 119.

Dumitrescu Eugenia, PhD, DVM, Professor, Departments of Pharmacology and Pharmacy, Faculty of Veterinary Medicine, University of Life Sciences “King Michel I of Romania” from Timisoara, 300645, Timisoara, Romania, Calea Aradului 119.

Mihai Folescu, PhD student, assistant Professor at Departments of Pharmacology and Pharmacy, Faculty of Veterinary Medicine, University of Life Sciences “King Michel I of Romania” from Timisoara, 300645, Timisoara, Romania, Calea Aradului 119.

Daiana Cocoș, PhD student, Assistant Professor at Departments of Biochemistry, Faculty of Veterinary Medicine, University of Life Sciences “King Michel I of Romania” from Timisoara, 300645, Timisoara, Romania, Calea Aradului 119.

Muselin Florin, PhD, DVM, MS, Professor, Department of Toxicology, Faculty of Veterinary Medicine, University of Life Sciences “King Michel I of Romania” from Timisoara, 300645, Timisoara, Romania, Calea Aradului 119; Romanian Academy-Branch Timisoara, 300223, Timişoara, România, Bv. Mihai Viteazu 24.

The article was submitted 08.07.2025; approved after reviewing 22.09.2025; accepted for publication 15.12.2025.