Svetlana V Notova, Olga V Marshinskaya, Tatyana V Kazakova

Animal Husbandry and Fodder Production. 2023. Vol. 106, no 1. Р. 183-191.

 

doi:10.33284/2658-3135-106-1-183

 

Review article

The role of trace elements in the antioxidant defense system of organism (review)

 

Svetlana V Notova1, Olga V Marshinskaya2, Tatyana V Kazakova3

1,2,3Orenburg State University, Institute of Bioelementology, Orenburg, Russia

1snotova@mail.ru, https://orcid.org/0000-0002-6378-4522

2m.olja2013@yandex.ru, https://orcid.org/0000-0002-5611-5128

3vaisvais13@mail.ru, https://orcid.org/0000-0003-3717-4533

 

 Abstract. The balance between free radicals and antioxidants is a fundamental link for the proper physiological functioning of organism. However, the antioxidant defense system is disrupted when living conditions are violated, which leads to an excessive increase in production of reactive oxygen species and free radical oxidation processes. The constancy of the chemical composition is important for the normal functioning of the antioxidant system. Despite their low content, trace elements are essential for the normal functioning of the body due to their diverse biological role. The homeostasis in a number of trace elements underlies between the dynamic of oxidative stress and antioxidants interaction in many pathophysiological processes. Both deficiency and excess of trace elements can affect the redox balance. Current review provides brief information about the nature, types and sources of free radicals, as well as the role of selenium, zinc, copper and iron in the antioxidant defense system.

Keywords: oxidative stress, reactive oxygen species, antioxidants, selenium, zinc, copper, iron

Acknowledgments: the  work  was  supported  by  the  Russian  Science   Foundation, Project No. 22-25-00600.

For citation: Notova SV, Marshinskaya OV, Kazakova TV. The role of trace elements in the antioxidant defense system of organism (review). Animal Husbandry and Fodder Production. 2023;106(1):183-191. (In Russ.). https://doi.org/10.33284/2658-3135-106-1-183

 

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Information about the authors:

Svetlana V Notova, Dr. Sci. (Medicine), Professor, Professor of the Department of Biochemistry and Microbiology, Chief Researcher of the Institute of Bioelementology, Orenburg State University, 13 Pobedy Ave, Orenburg, 460018, tel.: +7 (3532) 37-24-82

Olga V Marshinskaya, Junior Researcher, Institute of Bioelementology, Orenburg State University, 13 Pobedy Ave, Orenburg, 460018, tel.: +7 (3532) 37-24-82

Tatyana V Kazakova, Junior Researcher, Institute of Bioelementology, Orenburg State University, 13 Pobedy Ave, Orenburg, 460018, tel.: +7 (3532) 37-24-82

 

The article was submitted 27.02.2023; approved after reviewing 16.03.2023; accepted for publication 20.03.2023.

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