Kosyan DB, Surundayeva LG, Rusakova EA.
Research was carried out according the plan of research scientific works on 2019-2021 yy. FSBSI FRC BST RAS (No 0761-2019-0009)Interconnection of BGH gene polymorphism and lipid metabolism indices of the Hereford cattle
Dianna B Kosyan, Lyubov G Surundayeva, Elena A Rusakova
Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences (Orenburg, Russia)
Summary. The analysis of the relationship of bGH gene polymorphism with lipid metabolism indices and the estimation of the frequency of bGH gene occurrence in Hereford bulls was carried out. Analysis of genotype distribution showed that 12,2% of individuals have a desirable bGHGG genotype, a heterozygous state is characteristic of bGHGC 33.3%, and bGHCC is characteristic – of 54,5%. The gene balance in the population was not disturbed. It was noted that the content of saturated fatty acids in the samples differs depending on the genotype. In the control group, palmitic acid content prevails by 4,2% in comparison with the group of meat samples with heterozygous manifestation of the trait, and by 7,6% in animal meat samples with the desired genotype. In animal meat samples with the bGHGG genotype, which is desirable, stearic acid content prevails by 12,9% compared to animal meat samples with bGHGC genotypes and 8,4% – with the bGHСС genotype. When evaluating monounsaturated fatty acids (MNFА), it was noted that meat samples of animals with the desired genotype differ in the content of oleic acid.
It is established that testing of alleles of the bGH gene gene is of interest for taking into account the genetic potential of animals in several parameters of meat productivity, namely: growth rate, large carcass weight, meat yield, marbling of meat.
Key words: gobies,Hereford breed, bullhead, polymorphism, bGH gene, lipid metabolism, fatty acid composition.
- GOST R 55483-2013. Meat and meat products. Determination of fatty acids composition by gas chromatography. Enter. 2014-07-01. Moscow: Standartinform; 2014. 16 p.
- Zinovieva NA, Kostyunina OV, Gladyr EA, Bannikova AD, Kharzinova VR, Larionova PV, Shavyrina KM, Ernst LK. The role of DNA markers of signs of productivity of farm animals. Zootechniya.2010;1:8-10. (In Russ)].
- Surundaeva LG. Maevskaya LA, Kosyan DB. The use of DNA markers to detect polymorphism CAPN1 on beef breeds. Herald of Beef Cattle Breeding.2012;4(78):41-45.
- Gladyr EA, Zinov'eva NA, Kosyan DB, Volkova VV, Goncharenko GM, Soloshenko VA, Karpov AP, Ernst LK, Brem G.Characteristic of cattle allelepool for several meat breeds bred in the Southern Urals and Western Siberia. Achievements of Science and Technology of AIC. 2013;3:61-63.
- Arango JG, Echeverri ZJ, López HA. Association of the bovine growth hormone gene with Holstein cattle reproductive parameters. Rev MVZ Córdoba. 2014;19(3):4249-4258.
- Ardiyanti A, Abe T, Tameoka N, Kobayashi E, Shoji N, Ohtani Y, Suzuki K, Roh SG, KatohK. Effects of growth hormone gene polymorphism on lipogenic gene expression levels in diaphragm tissues of Japanese black heifers. Asian-Australas J Anim Sci. 2012;25(8):1055-1062. doi: https://doi.org/10.5713/ajas.2012.12029
- Dybus A, Grzesiak W, Kamieniecki H, Szatkowska I, Zbigniew S, Błaszczyk P, Czerniawska-Piątkowska E, Zych S, Muszyńska M. Association of genetic variants of bovine prolactin with milk production traits of Black-and-White and Jersey cattle. Archiv fur Tierzucht. 2005;48(2):149-156. doi: 10.5194/aab-48-149-2005
- Etherton TD, Bauman DE. Biology of somatotropin in growth and lactation of domestic animals. Physiological Reviews. 1998;78(3):745-761. doi: https://doi.org/10.1152/physrev.19188.8.131.525
- Ge W, Davis ME, Hines HC, Irvin KM, Simmen RCM. Association of single nucleotide polymorphisms in the growth hormone and growth hormone receptor genes with blood serum insulin-like growth factor I concentration and growth traits in Angus cattle. J Anim Sci. 2003;81(3):641-648. doi: https://doi.org/10.2527/2003.813641x
- Grossi DA, Buzanskas ME, Grupioni NV, Schenkel FS, Paz CCP, Regitano LC, Alencar MM, Munari DP. Effect of IGF1, GH, and PIT1 markers on the genetic parameters of growth and reproduction traits in Canchim cattle. Mol Biol Rep. 2015;42(1):245-251. doi: https://doi.org/10.1007/s11033-014-3767-4
- Hartatik T, Putra DE, Volkandari SD, Kanazawa T,SumadiS. Genotype analysis of partial growth hormone gene (GH891|MspI) in Pesisir cattle and Simmental-Pesisir crossbred cattle. J Indonesian Trop Anim Agric. 2018;43(1):1-8. doi: https://doi.org/10.14710/jitaa.43.1.1-8
12 Kim NK, Seo YW, Kim GH, Joh JH, Kim OH, Chung ER, Lee CS. A previously unreported Dral polymorphism within the regulatory region of the bovine growth hormone gene and its association with growth traits in Korean Hanwoo cattle. Anim Genet. 2004:35(2):152-154. doi: https://doi.org/10.1111/j.1365-2052.2004.01100.x
- Schlee P, Graml R, Schallenberger E, Schams D, Rottmann O, Olbrich-Bludau A, Pirchner F. Growth hormone and insulin-like growth factor I concentrations in bulls of various growth hormone genotypes. Theor Appl Genet. 1994;88(3-4):497-500. doi: https://doi.org/10.1007/BF00223667
- Tatsuda K, Oka A, Iwamoto E, Kuroda Y., Takeshita H., Kataoka H., Kouno S. Relationship of the bovine growth hormone gene to carcass traits in Japanese black cattle. J Anim Breed Genet. 2008;125(1);45-49. doi: https://doi.org/10.1111/j.1439-0388.2007.00688.x
- Yao J, Aggrey SE, Zadworny D, Hayes JF, Kühnlein U. Sequence variations in the bovine growth hormone gene characterized by single-strand conformation polymorphism (SSCP) analysis and their association with milk production traits in Holsteins. Genetics. 1996;144(4):1809-1816.
Kosyan Dianna Bagdasarovna, Cand. Sci. (Biol.), Leading Researcher, Laboratory for Breeding and Genetic Research in Animal Husbandry, Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, 460000, Orenburg, Russia, 29, 9 Yanvarya St., tel.: 8(3532)30-81-77, e-mail: email@example.com
Surundayeva Lyubov Gennadyevna, Cand. Sci. (Agr.), Associate Professor, Head of the Laboratory of Genetic Examination and Books of Breeding Animals, Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, 460000, Orenburg, Russia, 29, 9 Yanvarya St., tel: 8(3532)30-81-72, e-mail: firstname.lastname@example.org
Rusakova Elena Anatolyevna, Cand. Sci. (Biol.), Senior Researcher, Laboratory for Breeding and Genetic Research in Animal Husbandry, Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, 460000, Orenburg, Russia, 29, 9 Yanvarya St., e-mail: email@example.com
Received: 14 November 2019; Accepted: 16 December 2019;Published: 31 December 2019