Sheyda E.V, Lebedev S.V, Miroshnikov S.A, Grechkina V.V, Levakhin G.I.

 DOI: 10.33284/2658-3135-103-3-190

UDC 636.084:577.17:591.11

Acknowledgements:

The research was carried out with the support of the Russian Science Foundation. FSBSI FRC BST RAS (No. 20-16-00088)

Influence of ultrafine Fe on biochemical status of organism and exocrine activity of pancreas

against the background of feeding with protein diets in raising cattle

Elena V Sheyda1,2, Svyatoslav V Lebedev2, Sergey A Miroshnikov2, Victoria V Grechkina2,3,

Georgy I Levakhin2

1Orenburg State University (Orenburg, Russia)

2 Federal Research Centre оf Biological Systems and Agrotechnologies of the Russian Academy of Sciences (Orenburg, Russia)

3Orenburg State Agrarian University (Orenburg, Russia)

Summary. Тhe paper studied the effect of ultrafine particles of iron on the exocrine activity of the pancreas and changes in the biochemical parameters of blood against the background of protein components introduced into the diets: sunflower meal and soybean meal. The studies were carried out on calves of the Kazakh white-headed breed with an average weight of 120-130 kg, at the age of 8 months, with the imposition of a fistula in the pancreatic duct according to the original method. For the study, we used Fe UFPs (d = 90 nm, Z-potential 7.7 ± 0.5 mV) that contained 99.8% Fe. In the course of the study, it was found that the introduction of Fe UFP against the background of the use of protein diets in feeding cattle stimulates the exocrine activity of the pancreas, increasing the level of lipolytic activity and the activity of intestinal proteases. The positive effect of ultrafine particles on the course of carbohydrate, protein and mineral metabolism was registered.

Key words: cattle, feeding, ultrafine particles, iron, biochemical analysis, blood, pancreas, enzymes, pancreatic juice, chime.

References

  1. Zenova N, Nazarova A, Polishchuk S. Nanocrystalline iron influence on growth and development cattle according. Dairy and Beef Cattle Breeding. 2010;1:30-32.
  2. Levakhin YuI, Nurzhanov BS, Ryazanov VA, Dzhulamanov EB. Changes in the microbiocenosis of the rumen and digestibility of the dry matter of the diet with the introduction of gobies together fatty addition of ultrafine  iron  particles.  Agrarian  Bulletin  of   the  Urals. 2020;01(192):53-59. doi: 10.32417/1997-4868-2020-192-1-53-59
  3. Lemeshevsky VO, Radchikov VF, Kurepin AA. Effect of quality protein in the feed on the enzymatic activity in the rumen and productivity growing steers. Niva Povolzhya. 2013;4(29):72-77.
  4. Maeda Н, Akaike T. Nitric oxide and oxygen radicals in infection, inflammation and cancer. Biochemistry. 1998;63(7):1007-1019.
  5. Yatsko NA, Radchikov VF, Gurin VK, Tsai VP. Local sources of energy and protein in the diets of breeding heifers. Scientific notes of the educational institution "Vitebsk Order" Sign of Honor "State Academy of Veterinary Medicine". 2011;47(1):471-474.
  6. Kalashnikov AP, et al. Standards and diets of farm animals: Ref. book. 3rd ed., rework. and add. Moscow: Agropromizdat; 2003:456 p.
  7. Ovcharenko EV. Productivity and metabolism in cows in connection with the level and quality of dietary protein. Physiological and biochemical bases for increasing the efficiency of protein use by ruminants: scientific works. VNIIFBiP. Borovsk; 1983;24:33-39.
  8. Sheiko IP. Organization of complete feeding of farm animals using organic trace nutrients. Zootechniya. 2015;1:14-17.
  9. Dashkov VN, Shvedko AF, Sheiko IP, Radchikov VF. Crimping and conservation of grain – the way to the profitability of animal husbandry. Belarusian Agriculture. 2004;3:21-22.
  10. Sineshchekov AD. Nutritional processes and their nervous regulation in farm animals. Abstracts of the VIII All-Union Congress of Physiologists, Biochemists, Pharmacologists. Moscow; 1955:736 p.
  11. Fisinin VI, Vertiprakhov VG, Grozina AA. The exocrine pancreatic function in chicken  (gallus gallusl.) fed diets containing different ingredients. Sel’skokhozyaistvennaya Biologiya[Agricultural Biology]. 2018;53(4):811-819. doi: 10.15389/agrobiology.2018.4.811eng
  12. Fitsev AI, Grigoriev NG, Gaganov AP. Modern assessment of energy and protein nutritional value of plant feed. Feed Production. 2003;12:29-32.
  13. Radchikov VF, Ganushchenko OF, Gurin VK, Shinkareva SL, Lyundyshev VA. Extruded enrichmentbased flax seeds and barley grits in calves'' diets. Proceedings of the National Academy of Sciences of Belarus. Agrarian series. 2015b;1:92-97.
  14. Radchikov VF, Glinkova AM, Bessarab GV, Cat AN, Akulich VA, Yatsko NA, Pilyuk SN. The effectiveness of feeding defecate in the diets of calves. Zootechnical Science of Belarus. 2015a;50(2):36-43.
  15. Al-Qushawi A, Rassouli A, Atyabi F, Peighambari SM et al. Preparation and characterization of three tilmicosin-loaded lipid nanoparticles: physicochemical properties and in-vitro antibacterial activities. J Pharm Res. 2016;15 (4):663-676.
  16. Beard JL. Iron biology in immune function, muscle metabolism and neuronal functioning. J Nutr. 2001;131(2S-2):568S-579S. doi: 10.1093/jn/131.2.568S
  17. Dauncey MJ, Katsumata M, White P. Nutrition, hormone receptor expression and gene interactions: implications for development and disease. Muscle development of livestock animals: physiology, genetics and meat quality. Pas MFW, Evertes ME, Haagsman HP, editors. Wallingford: CABI; 2004:411 p.
  18. Diniz WJdaS, Coutinho LL, Tizioto PC, Cesar ASM, Gromboni CF, Nogueira ARA, de Oliveira PSN, de Souza MM, Regitano LC de A. Iron Content Affects Lipogenic Gene Expression in the Muscle of Nelore Beef Cattle. PLOS ONE. 2016;11(8): е0161160. doi:10.1371/journal.pone.0161160
  19. Jampilek J, Kos J, Kralova K. Potential of nanomaterial applications in dietary supplements and foods for special medical purposes. Nanomaterials. 2019;9(2):296. doi: 10.3390/nano9020296
  20. Lebedev SV, Sheida E, Vertiprakhov V, Gavrish I, Kvan O, Gubaidullina I, Ryazanov V, Miroshnikov I. A study of the exocrinous function of the cattle pancreas after the introduction of feed with a various protein source in rations. Вioscience Research. 2019b;16(3):2553-2562.
  21. Lebedev SV, Gavrish IA, Shejda EV, Miroshnikov IS, Ryazanov VA, Gubajdullina IZ, Makaeva AM. Effect of various fats on digestibility of nutrients in diet of сalves. IOP Conf. Series: Earth and Environmental Science. 2019a;341:012066. doi:10.1088/1755-1315/341/1/012066
  22. Lieu PT, Heiskala M, Peterson PA, Yang Y. The roles of iron in health and disease. Mol Aspects Med. 2001;22(1-2):1-87. doi: 10.1016/s0098-2997(00)00006-6
  23. Liu K, Shen J, Cao Y, Cai C, Yao J. Duodenal infusions of isoleucine influence pancreatic exocrine function in dairy heifers. Arch Anim Nutr. 2018;72(1):31-41. doi: 10.1080/1745039X.2017.1396144
  24. Mateescu R. It is possible to genetically change the nutrient profile of beef. (Conference proceedigs) Beef improvement Federation Research Symposium & Annual Meeting. Beef Improvement Federation, editor. Lincoln, Nebraska; 2014:87-92.
  25. Mody VV, Siwale R, Singh A, Mody HR. Introduction to metallic nanoparticles. J Pharm Bioallied Sci. 2010;2(4):282-289. doi: 10.4103/0975-7406.72127
  26. Rao PJ, Naidu MM. Nanoencapsulation of bioactive compounds for nutraceutical food. Sustainable Agriculture Reviews. 2016;21:129-156. doi: 10.1007/978-3-319-39306-3_4
  27. Troncarelli MZ, Brandão HdeM, Gern JC, Guimarães AdeS et al. Nanotechnology and Antimicrobials in Veterinary Medicine. Microbial pathogens and strategies for combating them: science, technology and education. 2013;1:543-556.

Sheyda Elena Vladimirovna, Cand. Sci (Biol.), Researcher, Laboratory for Biological Testing and Expertises, Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, 460000, Orenburg, Russia, 29, 9 Yanvarya St.; Researcher, Experimental Biological Clinic, 460018, Orenburg, Russia, Orenburg State University, 13 Pobedy Ave, 8-922-862-64-02, e-mail: elena-shejjda@mail.ru

Lebedev Svyatoslav Valerevich, Dr. Sci. (Biol.), Leading Researcher, Laboratory for Biological Testing and Expertises, Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, 460000, Orenburg, Russia, 29, 9 Yanvarya St.,  tel.: 8-912-345-87-38, e-mail: lsv74@list.ru

Miroshnikov Sergey Aleksandrovich, Dr. Sci (Biol.), RAS Corresponding Member, Director, Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, 460000, Orenburg, Russia, 29, 9 Yanvarya St., tel.: 8(3532)30-81-70, e-mail: vniims.or@mail.ru

Grechkina Victoria Vladimirovna, Cand. Sci (Biol.), Researcher, Laboratory for Biological Testing and Expertise, Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, 460000, Orenburg, Russia, 29, 9 Yanvarya St., Associate Professor, Department of Noncommunicable Animal Diseases, Orenburg State Agrarian University, 460014, Orenburg, Russia, 18 Chelyuskintsev, St.,  tel.: 8-922-877-14-97, e-mail: Viktoria1985too@mail.ru

Levakhin Georgy Ivanovich, Dr. Sci. (Biol.), Professor, Chief Researcher of Department of Agricultural Animals Nutrition and Fodder Technology named after S.G. Leushin, FSBSI «Federal Research Center for Biological Systems and Agrotechnologies of the Russian Academy of Sciences», 460000, Russia, Orenburg, ul. 9 Yanvarya, 29, tel.: 8(3532)30-81-79

Received: 4 Аugust 2020; Accepted: 14 September 2020; Published: 30 September 2020

Download