Sizova E.A, Nechitailo K.S, Ivanischeva A.P, Ryabov N.I.

DOI: 10.33284/2658-3135-103-3-177

UDC 636.085:577.17

Acknowledgements:

This work was carried out with the financial support of the Russian Science Foundation, project No. 20-16-00078

The prospects of using ultra-dispersed forms of metals in animal feeding

             Elena A Sizova1,2, Kseniya S Nechitailo1, Anastasia P Ivanischeva1, Nikolay I Ryabov1

1 Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences (Orenburg, Russia)

2Orenburg State University (Orenburg, Russia)

Summary. The unique prospects of using ultrafine metal forms are largely determined by their rare biological properties and their ability to act as sources of trace elements in animal nutrition. Possessing the declared characteristics, they can compete with the inorganic forms that are part of premixes for farm animals. The aim of the study was to study the effectiveness of the ultrafine alloy of copper and zinc as a dispersed inorganic material in poultry feeding in comparison with the inorganic and organic forms of these elements. The application of this approach leads to a positive productive effect. The ultrafine form of metals increases the activity of aminotransferases, which is a criterion for characterizing the level of the involvement of amino acid parts in biochemical processes due to reverse transfer reactions. It is also an indicator of changes in the passage of cell membranes of internal organs. Moreover, the histological picture of the liver of the experimental groups is similar to the control. At the same time, the absence of oxidative stress confirms the dynamics of the activity of indicators of the antioxidant system of the blood, the concentrations of which did not exceed the control values. The replacement of copper and zinc sulfates in the diet of broiler chickens with an ultrafine alloy of these elements (group I) and organic form (group II) was accompanied by an increase in the pool of these elements in broiler chickens at the end of the experiment. In the experiment, the dependence of the accumulation of the element on the form of the introduced metal was found. Copper accumulates throughout the experiment with a statistically significant difference in the liver and feather in the experimental group I. The concentration of copper with the introduction of its organic form is close to control. The dynamics of zinc concentration in feathers has a general tendency to decrease with age in all groups. The use of an ultrafine alloy leads to an increase in the concentration of zinc in the liver by the end of the experiment. Thus, the ultrafine form can become an alternative to the inorganic and organic forms of the studied elements in the nutrition of poultry.

Key words: broiler chickens, feeding, zinc, copper, ultrafine form, trace elements, biochemical parameters, elemental composition, liver, feather.

References

  1. Fisinin VI, Egorov IA, Lenkova TN, Okolelova TM, Ignatova GV, Shevyakov AN, Panin IG, Grechishnikov VV, Vetrov PA, Afanas'ev VA, Ponomarenko YuA. Methodical instructions on optimization of compound feed recipes for agricultural poultry. Moscow: VNITIP; 2009:80 р.
  2. Trifonov GA, Sviridova NYu, Presnyakov KA, Kuleshov KA. Morphofunctional state of chicken liver when Selenopiranum is included in the diet. Bulletin of the Altai state agrarian University. 2009;11(61):59-62.
  3. Yausheva EV, Miroshnikov SA, Kosyan DB, Sizova EA. Fe Nanoparticles in combination with amino acids change productive and immunological parameters in broiler chickens. Agricultural Biology. 2016;51(6):912-920. doi: 10.15389/agrobiology.2016.6.912eng
  4. Nesterov DV, Miroshnikov SA, Sipaylova OYu, Lebedev SV, Biryukov AA, Rusakova EA, Sukhanova ON, Kvan OV, Rakhmatullin ShG. Method for assessing the elemental status of a bird by feather: pat. Ros. Federatsiya 2478956. Declared 24.10.11; published 10.04.13; Byul. Byul. No 10.
  5. Sizova EA, Miroshnikov SA, Lebedev SV, Levakhin YuI, Babichev IA, Kosilov VI. Comparative tests of ultrafine alloy, salts and organic forms of Cu and Zn as sources of trace elements in feeding broiler. Agricultural Biology. 2018;53(2):393-403. doi 10.15389/agrobiology.2018.2.393eng
  6. Fokina E.G., Roslyi I.M. Adaptive fermentemia: monograph. Saarbrucken: Lambert Academic Publishing; 2013:110 р.
  7. Shamsutdinova IR. Shamsutdinova IR. Тhe Influence of silver nanoparticles on some liver functions in animals. New science: a Theoretical and Practical view. 2015;5-3:22-25.
  8. Farag MR, Alagawany M, AbdEl-Hack ME, Arif M, Ayasan T, Dhama K, PatraA, Karthik K. Role of chromiumin poultry nutrition and health: Beneficial applications and toxic effects. International Journal of Pharmacology. 2017;13(7): 907-915. doi: 10.3923/ijp.2017.907.915
  9. Hajializadeh F, Ghahri H, Talebi A. Effects of supplemental chromium picolinate and chromium nanoparticles on performance and antibody titers of infectious bronchitis and avian influenza of broilerchickens under heat stress condition. Veterinary Research Forum. 2017;8(3):259-264
  10. Lind T, Lоnnerdal B, Stenlund H, Gamayanti IL, Ismail D et al. A community-based randomized controlled trial of iron and zinc supplementation in Indonesian infants: effects on growth and development. The American Journal of clinical nutrition. 2004;80:729-736. doi: 10.1093/AJCN/80.3.729
  11. Joshua PP, Valli C, Balakrishnan V. Effect of in ovo supplementation of nano forms of zinc, copper, and selenium  on  post-hatch  performance  of broilerchicken. Vet World. 2016;9(3):287-294. doi: 10.14202/vetworld.2016.287-294
  12. Miroshnikova E, Arinzhanov A, Kilyakova Y, Sizova E, Miroshnikov S. Antagonist metal alloy nanoparticles of iron and cobalt: impact on trace element metabolism in carp and chicken. Human and Veterinary Medicine. International Journal of the Bioflux Society. 2015;7(4):253-259.
  13. Mishra B, Patel BB, Tiwari S. Colloidal nanocarriers: a review on formulation technology, types and applications   toward   targeted   drug    delivery. Nanomed-Nanotechnol. 2010; 6(1):9-24. doi: 10.1016/j.nano.2009.04.008
  14. Mohammadi V, Ghazanfari S, Mohammadi-Sangcheshmeh A, Nazaran MH. Comparative effects of zinc-nano complexes, zinc-sulphate and zinc-methionine on performance in broilerchickens. British Poultry Science. 2015;56(4):486-493. doi: 10.1080/00071668.2015.1064093
  15. Mroczek-Sosnowska N, Lukasiewicz M, Wnuk A, Sawosz E, Niemiec J, Skot A et al. In ovo administration of copper nanoparticles and copper sulfate positively influences chicken performance. Journal of the Science of Food and Agriculture 2016;96(9):3058-3062. doi: 10.1002/jsfa.7477
  16. Ognik K, Sembratowicz I, Cholewińska E, Jankowski J, Kozlowski K, Juskiewicz J. The effect of administration of copper nanoparticles to chickens in their drinking water on the immune and antioxidant status of the blood. Animal Science Journal. 2018;89(3):579-588. doi: 10.1111/asj.12956
  17. Scott A, Vadalasetty KP, Lukasiewicz M, Jaworski S, Wierzbicki M, Chwalibog A, et al. Effect of different levels of copper nanoparticles and copper sulphate on performance, metabolism and blood biochemical profiles in broiler chicken. Journal of Animal Physiology and Animal Nutrition. 2018;102(1):364-373. doi: 10.1111/jpn.12754
  18. Shirsat S, Kadam A, Mane RS, Jadhav VV, Zate MK, Naushad M et al. Protective role of biogenic selenium nanoparticles in immunological and oxidative stress generated by enrofloxacin in broiler chicken. Dalton Transactions. 2016;45(21):8845-8853.doi: 10.1039/C6DT00120C
  19. Siddiqi KS, Ur Rahman A, Husen T, Husen A. Biogenic fabrication of iron/iron oxide nanoparticles and their application. Nanoscale research letters. 2016;11(1):498. doi: 10.1186/s11671-016-1714-0
  20. Sookoian S, Pirola CJ. Liver enzymes, metabolomics and genome-wide association studies: from systems biology to the personalized medicine. Gastroenterol. 2015;21(3):711-725. doi: 10.3748/wjg.v21.i3.711
  21. Yausheva E, Miroshnikov S, Sizova Е, Miroshnikova E, Levahin V. Comparative assessment of effect of cooper nano and microparticles in chicken. Oriental Journal of Chemistry. 2015;31(4):2327-2336. doi: http://dx.doi.org/10.13005/ojc/310461
  22. Zhang H, Ji Q, Huang C, Zhang S, Yuan B, Yang K, Ma YQ. Cooperative transmembrane penetration of nanoparticles. Sci Rep. 2015;27(5):10525. doi: 10.1038/srep10525
  23. Zhang J, Spallholz J.Toxicity of selenium compounds and nano-selenium particles. In: Casciano D, Sahu SC, editors. Handbook of Systems Toxicology. West Sussex, UK: John Wiley and Sons; 2011:1-15. doi: 10.1002/9780470744307.GAT243
  24. Zhao CY, Tan SX, Xiao XY, Qiu XS, Pan JQ, Tang ZX. Effects of dietary zinc oxide nanoparticles on growth performance and antioxidative status in broilers. Biol Trace Elem Res. 2014;160(3):361-367. doi: 10.1007/s12011-014-0052-2

Sizova Elena Anatolyevna, Dr. Sci (Biol.), Associate Professor, Head of Centre  “Nanotechnologies in Agriculture”, Federal Research Centre for Biological Systems and Agricultural Technologies of Russian Academy of Sciences, 460000, Orenburg, Russia, 29, 9 Yanvarya St., tel.: 8-912-344-99-07, e-mail: Sizova.L78@yandex.ru; Professor, Department of Biology and Soil Science, 460018, Orenburg, Russia, Orenburg State University, 13 Pobedy Ave.

Nechitailo Ksenia Sergeevna, 2nd year postgraduate student, Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, 460000, Orenburg, Russia, 29, 9 Yanvarya St.

Ivanishcheva Anastasia Pavlovna, 2nd year postgraduate student Laboratory Assistant Researcher of Centre “Nanotechnologies in Agriculture”,  Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, 460000, Orenburg, Russia, 29, 9 Yanvarya St., tel .: 8-987-843-58-22, e-mail: n79228964398@yandex.ua

Ryabov Nikolai Ivanovich, Dr. Sci. (Agr.), Leading Researcher, Department for Beef Cattle Technology and Beef Production, Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, 460000, Orenburg, Russia, 29, 9 Januarya St.

Received: 10 Аugust 2020; Accepted: 14 September 2020; Published: 30 September 2020

Download