Inara E Laryushina

DOI: 10.33284/2658-3135-103-4-160

UDC 576.8.078


Research was carried out according the plan of research scientific works on 2019-2021 yy. FSBSI FRC BST RAS (No 0526-2019-0002)

The main mechanisms of "quorum sense" and their implementation in

       multimicrobial community (review)

Inara E Laryushina

Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences (Orenburg, Russia)

Summary. The study of the molecular mechanisms of quorum sensing today, undoubtedly, remains an urgent and demanded task. At the same time, the features of complex communication systems of the multi-microbial community are increasingly appearing in the focus of attention of leading research teams. Bacterial cells do not exist in isolation, and therefore relationships between bacterial systems, as well as with the host organism, are ubiquitous. The successful functioning of populations of microorganisms in the natural environment is largely due to a complex system of intercellular interaction. Communication of this kind is called Quorum Sensing (QS), which is a system for coordinating gene expression and depends on the density of the bacterial population, and its implementation occurs using small signaling molecules. Currently, a large number of microorganisms have been identified that have a sense of quorum. In addition, recent studies indicate that this process is also a mechanism for interspecies and interregnum interactions, including with higher eukaryotes. The review presents the molecular mechanisms underlying the biosynthesis of autoinducers, detection of intercellular signals, information processing, and post-transcriptional control of quorum sensing, as well as some ways of QS implementation in the multimicrobial community.

Key words: microorganisms, quorum sensing, multimicrobial community, interspecies interaction.


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Laryushina Inara Eskenderovna, Cand. Sci. (Med.), Researcher, Laboratory of Selection and Genetic Research in Livestock, Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, 460000, Orenburg, Russia, 9 Yanvarya St., 29, tel.: +79033658342, e-mail:

Received: 30 November 2020; Accepted: 14 December 2020; Published: 31 December 2020