Kristina S Kondrashova, Dianna B Kosyan, Kseniya N Atlanderova

DOI: 10.33284/2658-3135-103-4-128

UDC 636.085:636.085.25


Research was carried out according the plan of research scientific works on 2019-2021 yy. FSBSI FRC BST RAS (No 0526-2019-0002)

Effect of oak bark extract (Quercus cortex) and a complex of substances inhibitors Quorum sensing on metabolic processes occurring in the gastrointestinal tract of cattle

Kristina S Kondrashova, Dianna B Kosyan, Kseniya N Atlanderova

Federal Research Centre of Biological Systems and Agricultural Technologies of Russian Academy of Sciences (Orenburg, Russia)

Summary. One of trends in the practice of animal feeding in agriculture is the use of antibiotics as feed additives. However, they can have a negative impact on both the microflora of animals and the state of the environment. Therefore, there is a growing interest in finding alternative feed additives. In this regard, the article presents the results of a study conducted to determine the effect of Quercus cortex extract (I experimental group) and a complex of Quorum sensing inhibitors (II experimental group) on the digestibility of the feed substrate and metabolism in cattle, as an alternative feed additives to antibiotics. During the experiment, it was found that substances used positively affect the rate of nitrogen exchange, and an increase in the ammonia content in the rumen of animals of experimental groups I and II was noted to 2.88% and 8.80% (P≤0,001) (after 3 hours); 6.08% and 11.08% (P≤0,001) (after 6 hours), respectively. They also contribute to better digestibility of substances, as a result, the mass of digested dry matter of the experimental groups was superior to the control group by 3.02 % and 9.54 %, protein by 7.28% and 8.23%, fiber by 7.73% and 11.0%, in groups I and II, respectively. In addition, in the course of our research, a positive balance of nitrogen and calcium was established in all the compared groups. The phosphorus metabolism was more strongly influenced by the quorum sensing inhibitor drug than the Quercus cortex extract. At the same time, the deposition of phosphorus in group I compared to the control was higher by 16.99%, and in group II by 19.69%. The positive effect of the studied substances shows their prospects in the practice of animal husbandry.

Key words: cattle, digestibility, Quorum sensing, Quercus cortex extract, feeding, feed additives.


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Kondrashova Kristina Sergeevna, Junior Researcher at the Laboratories for Selection and Genetic Research in Animal Husbandry, Federal Research Centre of Biological Systems and Agricultural Technologies of the Russian Academy of Sciences, 460000, Orenburg, 29 9 Yanuarya st., tel.: +79228408002, e-mail:

Kosyan Dianna Bagdasarovna, Cand. Sci. (Biol.), I.O. Head of the Laboratory of Selection and Genetic Research in Livestock Breeding, Federal Research Centre of Biological Systems and Agricultural Technologies of the Russian Academy of Sciences, 460000, Orenburg, 29 9 Yanuarya st., tel.: +79228448915, e-mail:

Atlanderova Kseniya Nikolaevna, Cand. Sci. (Biol.), Junior Researcher, Test Centre CUC, Federal Research Centre of Biological Systems and Agricultural Technologies of the Russian Academy of Sciences, 460000, Orenburg, 29 9 Yanuarya st., tel.: +79228134865, e-mail:

Received: 12 November 2020; Accepted: 14 December 2020; Published: 31 December 2020