Nikolay P Gerasimov, Al’bek K Sangakov

Animal Husbandry and Fodder Production. 2024. Vol. 107, no 1. Р. 51-61.

 

doi:10.33284/2658-3135-107-1-51

 

Original article

Dynamics of weight growth in young Kazakh White-Headed breed with different levels

оf somatotropic axis gene expression

                                       

Nikolay P Gerasimov1, Al’bek K Sangakov2

1,2Federal Research Centrе of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, Orenburg, Russia

1nick.gerasimov@rambler.ru, https://orcid.org/0000-0003-2295-5150

2sangakovak@mail.ru, https://orcid.org/0009-0005-9843-4572

 

Abstract. The actual problem of MAS selection in beef cattle breeding is the selection of the most significant genes with guaranteed phenotypic effect on growth performance of beef cattle. The aim of the study was to evaluate the formation of live weight and average daily gain in young Kazakh White-Headed breed with different levels of somatotropic axis gene expression. Bulls (n=28) and heifers (n=22) were genotyped for IGF-1 C422T polymorphisms of the insulin-like growth factor gene, GH L127V of the growth hormone gene, and GHR F279Y of the growth hormone receptor gene. The data on the association of somatotropic axis genes with the growth rate in young animals of the Kazakh White-Headed breed were obtained. IGF-1 C472T and GH L127V polymorphisms had the greatest effect on live weight variability among the markers studied. In particular, the A-allele of the IGF-1 gene in the homozygous state was associated with maximum productivity in heifers up to one year of age, and in the heterozygous state - in bulls at 15 months of age. In turn, the VV genotype of the growth hormone gene is associated with increased body mass in bulls at weaning and at 12 months of age and in heifers at 15 months of age.

Keywords: Kazakh White-Headed breed, bulls, heifers, live weight, average daily gain, somatotropic axis gene

Acknowledgments: the work was performed in accordance to the plan of research works for 2023-2025 FSBSI FRC BST RAS (FNWZ-2021-0001).

For citation: Gerasimov NP, Sangakov AK. Dynamics of weight growth in young Kazakh White-Headed breed with different levels of somatotropic axis gene expression. Animal Husbandry and Fodder Production. 2024;107(1):51-61. (In Russ.). https://doi.org/10.33284/2658-3135-107-1-51

 

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Information about the authors:

Nikolay P Gerasimov, Dr. Sci. (Biology), Senior Researcher, Breeding and Genetic Center for Beef Cattle Breeds, Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, 29, 9 Yanvarya St., Orenburg, 460000, tel.: 8-912-358-96-17.

Al’bek K Sangakov, postgraduate student of Breeding and Genetic Center for Beef Cattle Breeds, Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, 29, 9 Yanvarya St., Orenburg, 460000.

The article was submitted 20.02.2024; approved after reviewing 06.03.2024; accepted for publication 18.03.2024.

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