Marina S Mingazova, Elena P Miroshnikova, Azamat Е Arinzhanov, Yulia V Kilyakova

Animal Husbandry and Fodder Production. 2024. Vol. 107, no 1. Р. 128-146.

 

doi:10.33284/2658-3135-107-1-128

Review article

General understanding of bacterial quorum sensing and use of quorum inhibitors in aquaculture (review)

 

Marina S Mingazova1,5, Elena P Miroshnikova2, Azamat Е Arinzhanov3, Yulia V Kilyakova4

1,2,3,4Orenburg State University, Orenburg, Russia

5 Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, Orenburg, Russia

1,5ms.mingazova@gmail.com, https://orcid.org/0000-0002-2818-1312

2elenaakva@rambler.ru, https://orcid.org/0000-0003-3804-5151

4arin.azamat@mail.ru, https://orcid.org/0000-0001-6534-7118

5fish-ka06@mail.ru, https://orcid.org/0000-0002-2385-264X

 

Abstract. The development of antibiotic resistance leads to the search for new solutions in the field of improving the quality of finished products and reducing the negative impact on the end user. Aquaculture being an actively developing industry imposes serious requirements on products, including reducing the incidence of diseases among farmed fish and reducing the use of antibiotics. Among the alternative drugs, there are various feed additives (pro-, prebiotics, phytogenic drugs) that can replace antibiotics without harm to the body of hydrobionts. A new branch is the study of quorum sensing bacteria and its effect on pathogenic organisms. Recent studies have shown that the use of quorum inhibitors can become a promising replacement for antibiotics without harm to the body and the end user. The main action of inhibitors is aimed at blocking the interaction of N-Acyl homoserine lactone with signaling receptors, which leads to inhibition of the expression of virulence-related genes. Scientists from different countries have conducted research on the effect of inhibitors on pathogenic bacteria for hydrobionts. The review presents information about quorum sensing of bacteria and general data on the study of quorum inhibitors that can become promising components in the feeding of hydrobionts.

Keywords: aquaculture, hydrobionts, fish, quorum sensing, quorum inhibitors, microbial community, pathogens

Acknowledgments: the   work   was  supported  by  the  Russian  Science   Foundation, Project No. 23-76-10054.

For citation: Mingazova MS, Miroshnikova EP, Arinzhanov AЕ, Kilyakova YuV. General understanding of bacterial quorum sensing and use of quorum inhibitors in aquaculture (review). Animal Husbandry and Fodder Production. 2024;107(1):128-146. (In Russ.). https://doi.org/10.33284/2658-3135-107-1-128

 

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Information about the authors:

Marina S Mingazova, Assistant of the Department of Biotechnology of Animal Raw Materials and Aquaculture, Orenburg State University, 13 Pobedy Ave, Orenburg, 460018, Postgraduate student of 2 year of study, Federal Research Centre of Biological Systems and Agrotechnologies of the Russian Academy of Sciences, 29, 9 Yanvarya St., Orenburg, 460000, tel.: 8-922-853-24-46.

Elena P Miroshnikova, Dr. Sci. (Biology), Professor, Head of the Department of Biotechnology of Animal Raw Materials and Aquaculture, Orenburg State University, 13 Pobedy Ave, Orenburg, 460018, tel.: 8-987-862-98-86.

Azamat E Arinzhanov, Cand. Sci. (Agriculture), Associate Professor, Associate Professor of the Department  of  Biotechnology  of  Animal Raw Materials and Aquaculture, Orenburg State University, 13 Pobedy Ave, Orenburg, 460018, tel.: 8-922-806-33-43.

Yulia V Kilyakova, Cand. Sci. (Biology), Associate Professor, Associate Professor of the Department  of  Biotechnology  of  Animal  Raw  Materials  and  Aquaculture,  Orenburg State University, 13 Pobedy Ave, Orenburg, 460018, tel.: 8-961-920-40-64.

The article was submitted 05.02.2024; approved after reviewing 16.02.2024; accepted for publication 18.03.2024.

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