Artemyeva OA, Dovydenkova MV, Berezova KA, Kolodina EN, Nikanova DA.

Animal Husbandry and Fodder Production. 2025. Vol. 108. No. 4. Р. 56-72.

doi:10.33284/2658-3135-108-4-56

Original article

Study of nonspecific resistance and clinical and biochemical status of broiler chickens

of the Smena 9 cross

 

Olga A Artemyeva1, Maria V Dovydenkova2, Ksenia A Berezova3, Evgeniya N Kolodina4,

Daria A Nikanova5

1,2,3,4,5Federal Research Center for Animal Husbandry named after Academy Member LK Ernst,

Dubrovitsy, Russia

1vijmikrob@mail.ru, https://orcid.org/0000-0001-7706-4182

2vijmikrob@mail.ru, https://orcid.org/0000-0002-3093-4117

3vijmikrob@mail.ru, https://orcid.org/0009-0005-9556-1947

4vijmikrob@mail.ru, https://orcid.org/0000-0002-4017-3390

5vijmikrob@mail.ru, https://orcid.org/0000-0001-5164-244X

 

Abstract. This study assessed the effect of a feed additive based on the carotene-containing yeast R. mucilaginosa on the physiological status and key parameters of non-specific resistance in broiler chickens of the Smena 9 cross. Three groups (one control and two experimental) with 26 animals in each were formed. The control group received the basic ration. The first experimental group received the basic ration daily with R. mucilaginosa yeast without freezing at a dose of 3 g / head / day, based on the calculation that the carotenoid content was 312 mcg / g in biomass. The second experimental group received the basic ration daily and R. mucilaginosa yeast after freezing, in the same dosage as the 1st experimental group. The results showed that the introduction of yeast, especially in frozen form, enhanced the parameters of nonspecific immunity. There was a significant increase in the bactericidal and lysozyme activity of blood serum, as well as the phagocytic activity of neutrophils, which is associated with an improvement in the bioavailability of immunoactive components (β-glucans, mannans) after freezing. At the same time, the supplement did not cause negative changes in hematological and biochemical parameters of the blood, which, in turn, remained within the physiological norm. Thus, Rhodotorula mucilaginosa yeast is an effective and safe probiotic supplement that supports the homeostasis of broiler chickens. Pre-heat treatment (freezing and defrosting) contributed to the destruction of the yeast wall and the release of intracellular contents with a complex of carotenoids.

Keywords: broiler chickens, «Smena 9», feeding, Rhodotorula mucilaginosa, biochemical parameters, hematology, non-specific resistance

Acknowledgments: this  work  was  supported  by  the  Russian  Science  Foundation,  Project  No. 23-16-00167. The authors are grateful to the Federal Scientific Center «All-Russian Research and Technological Institute of Poultry Breeding» of the Russian Academy of Sciences and the «Smena» Breeding and Genetic Centre. We extend our personal thanks to ZhV Emanuilova for her consultation and for providing the research object – the «Smena 9» domestic selective breeding cross.

For citation: Artemyeva OA, Dovydenkova MV, Berezova KA, Kolodina EN, Nikanova DA. Study of nonspecific resistance and clinical and biochemical status of broiler chickens of the Smena 9 cross. Animal Husbandry and Fodder Production. 2025;108(4):56-72. (In Russ). https://doi.org/10.33284/2658-3135-108-4-56

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Information about the authors:

Olga A Artemyeva, Cand. Sci. (Biology), Leading Researcher at the Microbiology Laboratory, Moscow  Federal  Research  Center  for  Animal  Husbandry  named  after Academy Member LK Ernst, 60 Dubrovitsy village, Podolsk City district, Moscow region, 142132,, tel.: 8(4967)651133.

Maria V Dоvydenkova, Cand. Sci. (Agriculture), Researcher at the Microbiology Laboratory, Federal Research Center for Animal Husbandry named after Academy Member LK Ernst, 60 Dubrovitsy village, Podolsk City district, Moscow region, 142132, tel.: 8(4967)651133.

Ksenia A Berezova, Junior Researcher, Microbiology Laboratory, Federal Research Center for Animal Husbandry named after Academy Member LK Ernst, 60 Dubrovitsy village, Podolsk City district, Moscow region, 142132, tel.: 8(4967)651133.

Evgeniya N Kolodina, Cand. Sci. (Biology), Senior Researcher at the Microbiology Laboratory, Federal Research Center for Animal Husbandry named after Academy Member LK Ernst, 60 Dubrovitsy village, Podolsk City district, Moscow region, 142132, tel.: 8(4967)651133.

Daria A Nikanova, Cand. Sci. (Biology), Senior Researcher at the Microbiology Laboratory, Federal Research Center for Animal Husbandry named after Academy Member LK Ernst, 60 Dubrovitsy village, Podolsk City district, Moscow region, 142132, tel.: 8(4967)651133.

Conflict of interests: the authors declare no conflict of interest. The authors declare that there is no conflict of interest. Commercial and financial organizations were not involved in the development of the study, the collection, analysis, or interpretation of data, the writing of the manuscript, or the decision to publish the results.

The article was submitted 01.09.2025; approved after reviewing 12.10.2025; accepted for publication 15.12.2025.  

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