Peglivanyan GK, Romanova EA, Tulinova OV.

Animal Husbandry and Fodder Production. 2026. Vol. 109. No. 1. Р. 71-81.

doi: 10.33284/2658-3135-109-1-71

Original article

Analysis of the kappa-casein (CSN3) genetic polymorphism in the Saanen goat population of the Leningrad region using the BLUP method

 

Grigory K Peglivanyan1, Elena A Romanova2, Olga V Tulinova3

1.2,3Russian Research Institute of Farm Animal Genetics and Breeding – Branch of the LK Ernst Federal Science Center for Animal Husbandry, St. Petersburg, Tyarlevo, Russia

1Peglivanian_grig@mail.ru, https://orcid.org/0000-0001-5194-4851

2splicing86@gmail.com, https://orcid.org/0000-0002-4225-5533

3tulinova_59@mail.ru, https://orcid.org/0009-0005-5704-4420

Abstract. Identifying genetic factors affecting milk quality and quantity is crucial for developing high-yielding dairy goat herds. Genetic markers are increasingly being used in modern breeding, significantly accelerating the selection of animals with valuable agricultural traits and increasing the efficiency of breeding efforts. This study examines a polymorphism at position 86209304 (TC substitution in exon 4) of the kappa-casein gene on chromosome 6 using PCR-RFLP analysis. Blood samples from 110 goats were analyzed for genotype frequencies: TT (frequency 0.65), TC heterozygotes – 0.35, and CC homozygotes were not detected. The study also examines the relationship between genotypes and economically important phenotypic traits. No statistically significant differences were found between the genotype groups, although some trends were noted in fat content, lactation stability and EBV assessment for milk yield (+12 and +15 versus +7 kg) in goats with the heterozygous TC genotype, which may be a confirmation of the higher genetic productive potential of this group of animals.

Keywords: goats, Saanen breed, kappa-casein, polymorphism, BLUP

Acknowledgments: the work was supported in accordance to the plan of research works for  2024-2026 RRIFAGB (№ 124020200029-4).

For citation: Peglivanyan GK, Romanova EA, Tulinova OV. Analysis of the kappa-casein (CSN3) genetic polymorphism in the Saanen goat population of the Leningrad region using the BLUP method. Animal Husbandry and Fodder Production. 2026;109(1):71-81. (In Russ.)]. https://doi.org/10.33284/2658-3135-109-1-71

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Information about the authors:

Grigory K Peglivanyan, Junior Researcher Laboratory of Molecular Genetics, Russian Research Institute of Farm Animal Genetics and Breeding – Branch of the LK Ernst Federal Science Center for Animal Husbandry, St. Petersburg, Tyarlevo, Moscow highway, 55a, 196625, tel.: +7 (981) 7652181.

Elena A Romanova, Researcher Laboratory of Population Genetics and Animal Breeding, Russian Research Institute of Farm Animal Genetics and Breeding – Branch of the LK Ernst Federal Research Center for Animal Husbandry, St. Petersburg, Tyarlevo, Moscow highway, 55a, 196625, tel.: +77 (960) 250-18-98.

Olga V Tulinova, Cand. Sci. (Agriculture), Leading Researcher Laboratory of Genetics and Cattle Breeding, Russian Research Institute of Farm Animal Genetics and Breeding – Branch of the LK Ernst Federal Research Center for Animal Husbandry, St. Petersburg, Tyarlevo, Moscow highway, 55a, 196625, tel.: +7 (921) 305-80-06.

The article was submitted 11.12.2025; approved after reviewing 06.02.2026; accepted for publication 16.03.2026.

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